The Science

The biology of skin aging

Skin aging is part of life. As we age, our skin changes-wrinkles, dryness, age spots, blemishes, and uneven skin tone starts to appear, and our skin might not be as elastic, smooth, and glowing as compared to our teenage years. While aging is unavoidable for it comes naturally, knowing the underlying biology of this process helps Zone-365 Beauty produce Natural and Organic Skincare Products that help slow down and reverse the process of skin aging.

What Causes Skin Aging: Intrinsic Aging and Extrinsic Aging?

Being the largest organ of the body, our skin is extremely exposed to the outer environment, making it more susceptible to intrinsic and extrinsic factors. Intrinsic aging is the natural process our skin is subject to go through as we get older. We all know that as we age, our body functions deteriorate. This factor is associated with slower cell replenishment, breakdown of fibroblast tissues responsible for the production of collagen, elastin, and glycosaminoglycan (GAG), dehydration, and reduced vascular and glandular network within the skin. Talking about slower cell replenishment, our body has special cells called stem cells, which possess a unique ability to develop into any type of cell that has damaged, grown, or lost. Stem cells have the special ability to divide themselves over and over again and produce new cells that can change into other types of cells needed to be replaced and reproduced. However, because of the passage of time, stem cells begin to lose efficiency and effectiveness in compensating and replenishing the cells or tissues that are being damaged and dying.

As we age, the population of fibroblasts decreases which results in reduced skin cell production of collagen, elastin, and glycosaminoglycan. The decrease in the production of these fibers that are essential for skin elasticity and skin repair causes the skin to lose fats, become thinner, and to lose its elasticity. As this happens, the skin shows visible and obvious signs of aging.


While intrinsic aging is inevitable, extrinsic aging which pertains to lifestyle and environmental factors that highly magnify the process of aging is preventable. Extrinsic aging factors include sun UV rays overexposure, smoking, poor diet, air pollution, and other environmental stressors, lack of sleep, and sleep position, as well as your repetitive facial movements and expressions. These factors can speed up aging which means that your skin could appear older than your genetic age especially if you're not doing anything to protect your skin from these avoidable factors.

Zoom-365 Beauty Solutions from Nature

The Power of Apple Stem Cell Technology Combined with Other Plant-Derived Antioxidants

Uncovering the factors that cause skin aging and the external factors that accelerate its process, Zone-365 Beauty's Research and Development team continues to formulate the best ingredients for Natural Skincare Products that help to combat the extrinsic aging factors and minimize the impacts of intrinsic aging in the skin.

As our company is committed to offering you skincare products that are organic and natural, and free from any harsh chemicals that harm the skin and environment, we make sure that all our ingredients are only derived from nature.

Being inspired by how stem cells function in our body, we have made the secondary metabolites produced by apple stem cells as the major active ingredient in all our Anti-Aging Skincare Products. Studies and research prove that these plant extracts can influence the skin positively, leading to improved skin conditions and healing. Plant stem cells have shown remarkable results in skin regeneration by helping the cells and tissues recover after an injury or imperfection. There are numbers of benefits when apple stem cells are introduced to your skin.

Here are among the few positive effects:

  • Strengthen and lengthens skin stem cell life
  • Aids fibroblast stimulation
  • Combats intrinsic aging in skin cells
  • Protect the skin from inflammation
  • Contributes to the repair and rebuild of impaired tissues
  • Enhances the body’s own skin stem cell regeneration
  • Prevents human stem cells from damage against UV light exposure and other environmental stressors


Our apple stem cell is formulated and manufactured with the highest standards. Our U.S. facilities are top-notch, where cleanliness and strict quality controls are secured at all times. Derived from pure plant extract, we have the finest apple stem cell to offer and made available for you across all our products. The power of apple stem cells combined with other plant-derived antioxidants such as vitamin c, vitamin e along with retinol and hyaluronic acid in the right amount and formulation, enables our natural anti-aging skincare products to protect the skin cells from damages caused by free radicals and UV rays, moisturize the surface of the skin, boost collagen and elastin production, and overall, reverse the signs of aging.

Certifications of our natural anti-aging skincare products

Certification for Hyaluronic Acid Serum Intla

Certification for Collagen Serum

Certification for Vitamin C Serum + Hyaluronic Acid

Certification for Rejuvenating
Night Serum

Certification for C.E Ferulic Brightening Serum

ZONE 365 Apple Stem Cell Beauty Care System is an all-new breakthrough for skincare. Formulated with natural ingredients, all our serums and creams are blended with apple stem cells to increase our products' potency, hence providing the best results you need.

The efficacy of our natural formula is evident in our customers’ experience with any of our serums and creams in just two weeks of use. The inclusion of apple stem cells in all our products has contributed to more meaningful results that our customers enjoy.

Combat the factors that cause and accelerate the appearance of skin aging efficiently, effectively, and safely with Zone-365 Beauty's Natural and Organic Skincare Products!

Keep your skin healthy, radiant, and glowing so you can let your natural beauty shine despite the passage of time.

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